PRP for Skin Rejuvenation

Conveniently located to serve the areas of Wyomissing PA and Reading PA

PRP Wyomissing

Platelet-rich plasma (PRP) for skin rejuvenation is a process that uses your body’s own restorative chemicals to reverse signs of aging, boost natural collagen production, and promote a younger, healthier appearance for your skin. This treatment extracts platelets and growth factors from your blood. Then, those restorative properties are applied over micro-channels that are made in your skin. Once they are reintroduced into your skin, these restorative chemicals trigger collagen production and cell turnover, replacing damaged skin cells with fresh, healthier cells. Because of this, wrinkles, fine lines, hyperpigmentation, and even acne scars can all fade, leaving behind smoother skin. Due to all of its wonderful benefits, Alyce Versagli is proud to offer her Wyomissing clientele PRP for skin rejuvenation. To learn more about other PRP uses or find out what your PRP session will look like, please schedule a personal consultation with our friendly staff or give our offices a call at (610) 685-2565.

Science Behind PRP 

Platelet rich plasma Wyomissing

When an injury to the skin occurs, fibroblast cells in our dermis send newly produced collagen and growth factors to the wound site to help repair damaged tissue and replace injured or aging cells.[1] This process helps our skin heal any cuts, nicks, or scrapes. However, this process can be controlled and even enhanced with PRP. We first draw a little vial of the patient’s blood and send that blood through a centrifuge. Once it’s done, the blood is separated into two different layers: a red-blood-cell layer, and a plasma layer – the layer rich in platelets and white blood cells.[2] This layer is the platelet-rich plasma and contains more than 20 platelet-derived growth factors that activate fibroblast cells. Once reintroduced into your skin, these growth factors intensify the body’s natural healing response. Over time, the cells in our dermis are refortified or replaced, causing our skin to look tighter, brighter, and younger. 


Amplify Collagen Production

Collagen, the fibrous, tensile protein found in 70-80% of our skin, is necessary for firm, smooth skin.[3] Found inside our dermis, collagen fibers are strong rope-like bands that keep our skin taut yet flexible to the physical stressors of the external world. When these fibers are healthy, they stop our skin from wrinkling, creasing, and losing its elasticity. But, as we age, the cells responsible for maintaining our collagen production slow down, causing the collagen fibers in our dermis to become weak and damaged. With feeble collagen fibers, our skin begins to wrinkle and grow laxer. By the age of 50, when we have lost 30% of our natural collagen supply, our skin can appear weathered with various signs of aging. But with PRP, we can restore the health of your fibroblast cells, which will diminish signs of aging and return that radiant, youthful glow to your skin. 

Counteract Photoaging

While PRP can combat wrinkles, fine lines, and loose skin, studies show it can also diminish the appearance of photoaged skin. Unprotected, prolonged exposure to UV rays causes melanogenic activity, which causes skin pigmentation to intensify.[4] Over time, this melanogenic activity causes our skin to change in tone and texture, leading to the appearance of sunspots. Sunspots are brown, uneven dots in our skin that appear on any area that has experienced significant exposure to UV rays. To erase these brown spots, the restorative chemicals found in your PRP serum heal the damaged, discolored cells. Studies show that 6 months after an initial PRP treatment, sunspots, and uneven texture have significantly reduced from a patient’s complexion.[5]

Quick Procedure With Minimal Downtime

Because PRP for skin rejuvenation is only minimally invasive and requires a topical anesthetic to alleviate discomfort, you will be in and out of our care in no time. Once you are home, you can expect minimal recovery and downtime. After a day of letting the PRP serum absorb into your skin, you may cleanse your skin. AHA, BHA, and retinols must be avoided for one week. Any activities that cause sweating must be eliminated from your routine for 72 hours.


No two people age the same. Whether to diminish current signs of aging or as a preventative measure, PRP for skin rejuvenation is great for any patient of any age. If you wish to get rid of your wrinkles, fine lines, sunspots, or loose skin, PRP is a safe, effective solution to achieve your ideal aesthetic. If you would like to learn more or see if PRP is right for you, please schedule a personal consultation at our Wyomissing offices. 

Personal Consultation

Alyce Versagli opened SkinCare by Alyce with one goal in mind: provide safe, effective, long-lasting skincare treatments to her clients. For the last 25 years, that mission has not changed. With her expertise, knowledge, and skill, Alyce and her team pride themselves on giving their clients the best, most advanced, and advantageous skincare products, treatments, and services on the market. Coupling the best skincare options with the best care possible, SkinCare by Alyce gives many clients a completely rejuvenated appearance. To read about their experience, be sure to check out our reviews page!

Your Consultation

We will begin your consultation with a brief physical examination and a new patient intake interview. Next, Alyce will ask about your ideal appearance. She will want to learn about you as an individual and how you wish to appear. Alyce and her team believe in treating the patient not the problem, so we will aim to achieve a three-dimensional understanding of you and your areas of concern. Then, Alyce will walk you through our list of treatments and services, pointing out which ones she feels are best for your desired results. Be sure to ask any questions. If PRP for skin rejuvenation is selected, we will construct a personalized treatment plan and will outline your procedure. Before you leave our care, we will give you a list of preparatory steps that you should adhere to between now and the date of your PRP session. 


Before your PRP for skin rejuvenation session, you will need to:

Avoid unprotected, prolonged exposure to the sun or tanning beds. 

Stay well hydrated and well-nourished.

Arrive at your appointment without makeup


To start your PRP session, we will draw a small amount of your blood and then separate the platelets in a centrifuge. Then, we will treat the target area(s) with a topical anesthetic to numb the skin and keep you comfortable during your session. Next, we will microneedle the target area(s). Microneedling helps create channels in your skin for the PRP serum to absorb. Once the appropriate channels have been made in your skin, we will apply the PRP over the micro-holes using a lighter, less invasive needle setting. After this, a light moisturizer will be applied, and post-treatment instructions will be reviewed.


PRP Wyomissing

After your session, your skin will feel tingly and numb. Over the next couple of days, it is important to avoid UV exposure. Your skin is very sensitive at this stage, so please be mindful of protecting it. To further this protection, be sure to stay well hydrated, as proper hydration helps our skin retain elasticity and healing properties. For the next three days, be sure to avoid any strenuous activities and exercise. 


After a couple of weeks, you will notice your skin is gradually appearing younger, smoother, and brighter. Wrinkles, acne scars and fine lines have started to fade, and sunspots are subtly vanishing. After a couple of months, your skin will appear even in tone and texture, and troublesome wrinkles will be a sight of the past. For best results and to achieve a rejuvenated appearance, three treatments are recommended.

Cost in Wyomissing

The cost of your PRP skin rejuvenation procedure will vary depending on how many sessions you need to achieve your ideal results. We will determine the exact price of your treatment plan during your consultation. If you have any questions, please call our offices directly at (610) 685-2575.


  1. Cho, E. B., Park, G. S., Park, S. S., Jang, Y. J., Kim, K. H., Kim, K. J., & Park, E. J. (2019). Effect of platelet-rich plasma on proliferation and migration in human dermal fibroblasts. Journal of cosmetic dermatology, 18(4), 1105–1112.
  2. Roukis, T. S., Zgonis, T., & Tiernan, B. (2006). Autologous platelet-rich plasma for wound and osseous healing: a review of the literature and commercially available products. Advances in therapy, 23(2), 218–237.
  3. Oikarinen A. (1994). Aging of the skin connective tissue: how to measure the biochemical and mechanical properties of aging dermis. Photodermatology, photoimmunology & photomedicine, 10(2), 47–52.
  4. Handel, A. C., Miot, L. D., & Miot, H. A. (2014). Melasma: a clinical and epidemiological review. Anais brasileiros de dermatologia, 89(5), 771–782.
  5. Alam, M., Hughart, R., Champlain, A., Geisler, A., Paghdal, K., Whiting, D., Hammel, J. A., Maisel, A., Rapcan, M. J., West, D. P., & Poon, E. (2018). Effect of Platelet-Rich Plasma Injection for Rejuvenation of Photoaged Facial Skin: A Randomized Clinical Trial. JAMA dermatology, 154(12), 1447–1452.