Conveniently located to serve the areas of Wyomissing PA and Reading PA


Topical exosome use is an increasingly popular way to help your body rejuvenate and regenerate after a cosmetic procedure. Through tailored skin care treatments, patients can support skin hydration, promote an even tone and complexion, and see visible reconditioning of the skin. Skin Care by Alyce is proud to offer Exosomes by BENEV to promote skin healing and long-term skin health.

We are Wyomissing’s premiere specialty med spa and skincare boutique, led by one of Pennsylvania’s leading registered nurses and licensed aestheticians. Speak to Alyce Versagli BSN, RN about BENEV Exosome treatment as an add-on to one of her personalized skin health services. Contact us at (610) 685-2575 to book your personal consultation, or fill out a form online to get started.

About Exosomes

The passage of time can take its toll on our physical appearance. Fighting signs of aging and keeping your skin looking and feeling silky smooth is important. Similarly, blemish-prone skin and rough texture can be improved with targeted med spa treatments to improve skin health and appearance. Using the very latest nanoparticle technology, topical exosome application can help cell-to-cell communication and support a healthier, younger-looking complexion.

Scientists first discovered exosomes in the 1960s with further in-depth study occurring in the 1980s. In the years that followed, researchers learned more and more about them, and quickly realized their therapeutic potential. (1)

Studies have revealed the multiple roles exosomes play in bodily processes in the past few years. They are crucial in wound healing and skin health. They can be used in conjunction with cosmetic anti-aging services that improve the appearance and health of the skin. For example, treatments such as microneedling can be enhanced with exosomes, as the tiny microchannels made by the needles can deliver exosomes directly into the skin to aid skin restructuring. So what exactly are exosomes and how exactly can they help us achieve healthy, radiant skin?

What Are Exosomes?

Exosomes are tiny particles released by cells. They promote tissue regeneration. (2) Containing several key molecules, they can help the body to remodel and heal. They’re part of a family of particles called extracellular vesicles (EVs). EVs are tiny sac-like structures that contain fluid. They play an important role in the ability of cells to communicate with each other. They also transport nourishing “cargo” from cell to cell. 

The successful transfer of material between cells helps the body stay healthy. Communication between cells must be efficient in order for the body to function well, especially following illness or tissue trauma. The stronger the cell communication, the faster the body can heal and work optimally. So, EVs like exosomes are vital influencers of cell behavior and overall vitality.

Exosomes contain important substances that either activate or prevent certain pathways for the following cell processes:

  • Wound healing 
  • Skin matrix remodeling  
  • Changes in the body’s immune response
  • New blood vessel formation
  • Cell death prevention
  • Cell migration, growth, and differentiation (2)

What Can Exosomes Carry?

Exosomes can aid the exchange of important proteins and other key materials between cells. Exosome processes can involve:

  • Fibroblasts – The most common cell types in connective tissue, important for wound healing and tissue regeneration. (3)
  • Keratinocytes Play a key role in skin structure and defense. Powerful factors in the immune response.
  • Immune Cells Includes mast cells, macrophages, and neutrophils, essential for fighting infection and disease.
  • Growth Factors – Stimulate many different cell processes. Regulate and promote cell division and growth.
  • Cytokines – Small molecular messenger proteins that regulate inflammation and support immune response.
  • RNA – Ribonucleic acid (RNA) is part of our genetic code. Like DNA, it contains information important for multiple biological processes.

Eczema Case Study

A recent study has shown promising developments in understanding exosomes and how they can benefit the skin. In particular, they can be useful for the treatment of chronic skin conditions. Scientists studied the role that exosomes have on atopic dermatitis, otherwise known as eczema. Eczema can be a lifelong condition that is itchy, painful, and can cause significant physical and psychological stress. Researchers in South Korea found that exosomes promote skin barrier repair and aid in the restoration of skin barrier function. (4)

BENEV topical Exosomes can facilitate better cell-to-cell communication of vital materials so you can reap the aesthetic benefits with healthier, glowing skin!

ExoSCRT™ Technology

ExoSCRT™ is an innovative technology. It has the ability to separate and refine 0.1% pure exosomes from stem cells. Paraben-free and hypoallergenic, our topical add-ons by BENEV are topical solutions designed to be absorbed quickly by the skin to deliver the concentrated benefits of exosomes.

Please Note: Exosomes by BENEV and ExoSCRT technology are not drug products. They are not intended to prevent, treat or cure diseases or medical conditions. They are for topical use only following a prior skin treatment and are not intended to be injected or delivered intravenously.

Personal Consultation

With a personal skin analysis, you can discover more about the best ways to fight signs of aging and transform dull, textured skin. We also offer comprehensive skin treatment services for a range of common skin conditions. Alyce and her team appreciate that great skin treatments go a long way! And, at her boutique Wyomissing med spa, she provides a range of treatments to address your unique skin concerns. These include services for the following conditions:

  • Hyperpigmentation
  • Acne
  • Acne Scars
  • Sun Damage
  • Broken Capillaries
  • Dry Skin
  • Sensitive Skin
  • Blemished Skin
  • Brown Spots
  • Rosacea
  • Milia
  • Stretch Marks
  • Submental Fat
  • Hair Restoration

During your meeting with Alyce, you can discuss the treatments that interest you most. You can also find out if BENEV Exosome treatment can be added on to enhance your cosmetic results and strengthen your skin. After a thorough skin analysis, Alyce will choose the treatment or treatments that best fit your skin and personal aesthetic goals.

Please see our blog to read about the wide selection of skin treatments at Skin Care by Alyce.

Rejuvenating Skin Treatments

People come to Skin Care by Alyce for many reasons. Whether you’re coming for anti-aging treatment, blemish or scar care, skin texture improvement, or simply want to improve your skin’s overall brightness and hydration levels, Alyce can help you achieve your goals! 

Topical Exosomes can be added to the following skin treatments:


Microneedling procedures involve the precise application of many small needles onto the skin. These needles cause controlled micro-injuries that stimulate the skin’s regenerative properties deep within tissues. New collagen is formed, and the skin’s structural support system is strengthened. This can achieve healthier skin regeneration, a reduction in fine lines and wrinkles, and tighter, smoother skin. 

Laser Skin Treatment

Lasers can be used in many ways in skin care, including skin resurfacing, pigmentation correction, facial rejuvenation, and hair removal. Aesthetic lasers that employ Intense Pulsed Light (IPL) technology allow patients to achieve decreased redness, treat hyperpigmentation, and stimulate collagen. Erbium lasers can also provide minimally-invasive resurfacing solutions to help smooth skin and reduce the appearance of scars and blemishes.

Chemical Peel

Chemical peels remove dead skin cells and debris from the skin and reveal fresher, newer skin beneath. They can help reduce the appearance of wrinkles, address hyperpigmentation, and improve acne. Tailored formulations can be used in a number of areas of the body, including the face and neck, back, shoulders, lips, and hands. We offer a wide selection of chemical peels for your skin care needs. These include:

  • Glycolic Acid Peel
  • Salicylic Acid Peel
  • Mandelic Acid Peel
  • Jessner Peel
  • TCA Peel
  • Pyruvic Peel

Our chemical peels are formulated for maximum efficiency, and may be superficial, medium, or deep, depending on your needs.


Platelet Rich Plasma (PRP) can support healthier skin tone, increase collagen and elastin production, and add volume to tired tissues. PRP can be applied to the skin during microneedling to aid with the natural healing of the skin during recovery. A patient’s own blood is specially treated to extract platelets and growth factors. It is then reintroduced to the body as part of the microneedling treatment to achieve smoother, silkier skin.

Cost of Exosomes in Wyomissing, PA

Exosomes can be used as a post-treatment pick-me-up. Speak to Alyce about your topical Exosome add-on options for your skin procedure. Please feel free to inquire about Exosomes if you’re considering microneedling, aesthetic laser treatment, chemical peels, PRP, or other facial skin rejuvenation services. Call (610) 685-2575 or fill out a simple inquiry form to book your personal skin analysis at Skin Care by Alyce.

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  1. Yang GH, Lee YB, Kang D, et al. Overcome the barriers of the skin: exosome therapy. Biomaterials Research. 2021;25(1). http://www.doi.org/10.1186/s40824-021-00224-8 
  2. Dinescu S, Dobranici A, Tecucianu R, et al. Exosomes as Part of the Human Adipose-Derived Stem Cells Secretome- Opening New Perspectives for Cell-Free Regenerative Applications. Advances in Experimental Medicine and Biology. Published online 2020:139-163. https://www.doi.org/10.1007/5584_2020_588 
  3. Dick MK, Miao JH, Limaiem F. Histology, Fibroblast. PubMed. Published 2020. https://www.ncbi.nlm.nih.gov/books/NBK541065/#:~:text=The%20fibroblast%20is%20one%20of 
  4. Shin KO, Ha DH, Kim JO, et al. Exosomes from Human Adipose Tissue-Derived Mesenchymal Stem Cells Promote Epidermal Barrier Repair by Inducing de Novo Synthesis of Ceramides in Atopic Dermatitis. Cells. 2020;9(3):680. http://www.doi.org/10.3390/cells9030680